Mpox Information for Providers

Mpox is a rare viral disease not often seen in the United States. Anyone can get mpox. Most people recover in 2–4 weeks, but the disease can be serious, especially for children and people who are immune compromised or pregnant. For more general information, see our mpox page.

Immediately report suspected monkeypox cases.

Complete and fax an intake form to our confidential fax (253) 649-1389 and review exposure guidelines to evaluate close contacts.

Call Call (253) 649-1412, press 0 (M-F, 8 a.m.-4:30 p.m.). Or call the 24 hour Reporting Line: (253) 649-1413 and leave a message with the patient\'s first name, last name, date of birth. with any questions.

How to identify

It can be easy to miss mpox or mistake it for herpes, syphilis, folliculitis or an abscess. 

Early symptoms

  • Fever.
  • Malaise.
  • Headache.
  • Weakness.
  • Swollen lymph nodes.


  • Are well circumscribed, deep seated and often develop umbilication (dot on the top of the lesion).
  • Can be extremely painful.
  • Appear after fever.

Lesions tend to appear and develop at the same time on an affected area of the body—like pustules on face or vesicles on legs. They progress through 4 stages—macular, papular, vesicular and pustular—before they scab and heal in 1–2 weeks.


Mpox mostly spreads through close, physical contact, and is far less likely to be spread in the air.

The virus spreads through contact with:

  • Mpox rash, sores or scabs.
  • Objects, fabrics or surfaces a person with monkeypox used.
  • Respiratory droplets or oral fluids from a person with monkeypox.

Mpox can spread as soon as symptoms start until all sores heal and a fresh layer of skin forms. This can be several weeks.

Personal protective equipment (PPE)

When you interact with a patient, wear:

  • Gown.
  • Eye protection (i.e., goggles or a face shield that covers the front and sides of the face).
  • Gloves.
  • NIOSH-approved particulate respirator equipped with N95 filters or higher.

How to test

Use a PCR test to collect a sample.

  1. Collect 2 swabs from each lesion on 2 separate sites. Use synthetic swabs (i.e., Dacron, polyester, nylon). Do not use cotton swabs. Vigorously swab lesions. You don’t need to de-roof the lesion before swabbing.
  2. Break off the end of each swab’s applicator into separate screw-capped tube or place swabs in separate sterile containers or viral transport medium (VTM). Do not use universal or other transport media.
  3. Store samples at 2–8° C within an hour of collection. If the testing lab won’t receive the sample within 24 hours, freeze it. Coordinate a plan with your lab manager.

Submit to a lab.

Ask your lab if they test for mpox. Follow the lab’s sample collection procedure. Labs that currently test for mpox:

Washington has no shortage of mpox tests.

How to treat

Use tecovirimat (TPOXX) antiviral medication to treat people who are at high risk of severe disease. Learn more in Centers for Disease Control and Prevention’s (CDC’s) interim clinical guidance.


You’re eligible to get mpox vaccine if you:

1. Had a high-risk exposure to a person diagnosed with or exposed to mpox.
2. Are a gay, bisexual or other man or transgender person who has sex with men.
3. Exchanged sex for money, drugs or other purposes in the past 6 months. 
4. Used methamphetamine in the past 6 months. 
5. Were sexually assaulted. 
6. Had a new diagnoses in the last 12 months of one or more nationally reportable sexually transmitted diseases; such as acute HIV, chancroid, chlamydia, gonorrhea, or syphilis.
7. Are taking PrEP to prevent HIV infection.
8. Had multiple or anonymous sex partners in the last 6 months. 


  • For urgent issues, call (253) 649-1412.
  • For non-urgent issues, call (253) 649-1413 and leave a message.
    • Includes reporting notifiable conditions 24 hours a day, 7 days a week.
    • Leave the patient’s name, date of birth and disease.


For clinicians

For patients

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